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Project #1 Investigating the clinical efficacy of biological product doped pro-regenerative hydrogels in ocular surface chemical and thermal burn animal models

Project Power in Numbers

TÜBİTAK 1001

Funder

₺ 1,399,300

Grant Secured

4

Bursary Student(s)

Regenerative Contact Lens in Animal Models


Ocular surface chemical injuries mostly occur due to workplace-related injuries and/or accidents and constitute 7% to 18% of ocular emergency admissions. Despite intensive topical, systemic and, surgical treatments, the widespread damage in severe cases result in limbal stem cell (LSC) insufficiency and consequent severe visual loss. Interventions performed in the chronic stage (e.g. LSC transplantation, corneal transplantation) are costly and the long-term visual and anatomical results are oftentimes insufficient. 

In this follow-up project we aim to evaluate the safety and efficacy of our growth factor-enriched hydrogel biomaterial in two different ocular surface injury animal models.

This project is supported by the Scientific and Technological Research Council of Turkey (TÜBİTAK), Project Number: 123S073

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